Hong Jiang, MD, PhD, Displays Expertise in Translation from Scientific Breakthrough Discoveries to Effective Clinical Applications
Press Release February 6, 2025
Hong Jiang, MD, PhD, is the Founder, former Chairwoman of the Board of Directors and Chief Scientific Officer at Avotres Inc.
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her contributions have not only advanced the knowledge of immunology, but also provided hope for patients suffering from incurable immunologically related diseases globally.

FORT LEE, NJ, February 06, 2025 /24-7PressRelease/ -- Hong Jiang, MD, PhD, has been included in Marquis Who's Who. As in all Marquis Who's Who biographical volumes, individuals profiled are selected on the basis of current reference value. Factors such as position, noteworthy accomplishments, visibility and prominence in a field are all taken into account during the selection process.

Dr. Jiang, a distinguished Research Scientist and expert in basic and clinical immunology and also an entrepreneur, who has dedicated her career to discovering, investigating and validating the novel theory, "Avidity Model of peripheral T cell Regulation (Avotres Model)", on the mechanism of Q/E CD8+ Treg pathway that is, restricted by non-conventional and non-polymorphic MHC Class 1b molecule, functions to discriminate self from nonself in the periphery after normal thymic negative selection is completed in the thymus. Based on this discovery, the understanding and treatment of autoimmune diseases and many other immunologically related diseases, including prevention of recurrence of cancers and effective control of chronic rejection of graft transplantation in potential clinical applications, have been advanced. She has also developed the Avotres technology platforms, including the manufacture platforms of immunomodulatory drugs for the aforementioned therapeutic applications, and a unique diagnostic assay system for early auto-immune disease detection and monitoring. As a research scientist, and later, the Founder, Chairwoman of the Board of Directors and Chief Scientific Officer at Avotres Inc., she has been at the forefront of pioneering innovative therapies based on the breakthrough scientific discoveries. Her work with late Dr. Leonard Chess at Columbia University has set up the scientific foundation for the development of the Avotres innovative drug/therapies, opening up a new direction with new approaches in current T cell Biology and Biotech field.

Prior to her current role, Dr. Jiang served as a professor of clinical immunology at College of Physicians and Surgeons, Columbia University. During her tenure, she conducted groundbreaking research on Type 1 diabetes and many other distinct autoimmune diseases and contributed significantly to the field of immunology.

Laying the groundwork for Dr. Jiang's professional endeavors was her academic background. She earned a Medical degree in internal medicine from Anhui Medical University in 1975, a Master degree of Pathophysiology in 1982, and a Doctor degree of Philosophy in microbiology and immunology from the Columbia University, College of Physicians and Surgeons in 1993.

Reflecting upon her journey, Dr. Jiang attributes her success to her unwavering dedication and hard work, as well as the invaluable guidance of her mentors, the late Dr. Benvenuto Pernis and Dr. Leonard Chess. Their influence has been instrumental in shaping her career path and inspiring her passion for making a difference in the lives of innumerable individuals suffering from currently incurable immunologically related diseases. Her expertise in drug development and understanding of human adaptation to treatments have been pivotal in her professional achievements.

Dr. Jiang's contributions to medical science have not only advanced the knowledge of immunology, but also provided hope for patients suffering from those incurable immunologically related diseases globally. Looking ahead, she is committed to growing Avotres Inc., addressing real-life problems, and assisting people worldwide through innovative solutions. She plans to continue working while leveraging her strengths to further her company's mission of driving progress in this critical area of healthcare.

About Marquis Who's Who®:
Since 1899, when A. N. Marquis printed the First Edition of Who's Who in America®, Marquis Who's Who® has chronicled the lives of the most accomplished individuals and innovators from every significant field of endeavor, including politics, business, medicine, law, education, art, religion and entertainment. Who's Who in America® remains an essential biographical source for thousands of researchers, journalists, librarians and executive search firms around the world. The suite of Marquis® publications can be viewed at the official Marquis Who's Who® website, www.marquiswhoswho.com.

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